Cancer Biology and Therapeutics

Anti-Cancer Vaccines/drugs

Anti-Cancer monoclonal antibodies can be targeted against malignant cells by several mechanisms. Tissue-specific gene delivery using immune liposomes has also been achieved in brain, and breast cancer tissue. Antibody-directed enzyme pro drug therapy involves the application of cancer associated monoclonal antibodies which are linked to a drug-activating enzyme. Subsequent systemic administration of a non-toxic agent results in its conversion to a toxic drug, and resulting in a cytotoxic effect which can be targeted at malignant cells. A cancer vaccine is a vaccine that either treats existing cancer or prevents development of a cancer. Vaccines that treat existing cancer are known as therapeutic cancer vaccines. There are currently no vaccines able to prevent all cancers. However vaccines against some oncoviruses have proven extremely effective. Treatment often fails when cancer becomes resistant to anti-cancer drugs. Knowledge of all the human genes and their functions may allow effective preventive measures, and change drug research strategy and drug discovery development processes. This Session Includes Functional genomics in drug discovery and development, Therapeutic antibodies and cancer vaccines, Novel drug delivery system and cancer drug designing, Anticancer drugs in global market: economy and their cost effectiveness, Nanotechnology in cancer drugs, Cancer clinical trials, Regulatory issues in cancer research, Drug compounds targeting Tumor metabolism, CAR T-Cell Therapy, Oncolytic viral therapies , Gene therapy, Adoptive T-Cell transfer.